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KMID : 1201420130060010050
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Journal of Neurocritical Care
2013 Volume.6 No. 1 p.50 ~ p.53
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Concurrent Development of Systemic Lupus Erythematosus and Neuromyelitis Optica
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Park Hyun-Ju
Kwon Seok-Beom
Jung San
Hwang Sung-Hee
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Abstract
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Background: Neuromyelitis optica (NMO) is one of rare and serious neurological manifestations of systemic lupus erythematosus (SLE) and is diagnosed by optic neuritis, myelitis, 3 or more contiguous spinal cord segments involvement and seropositivity for anti-NMO IgG. We report a case of patient with NMO fully satisfied with Wingerchuck’s criteria as the first manifestation of SLE.
Case Report: A 30-yearold woman with two times of optic neuritis was admitted due to reduced vision, lower leg tingling sensation and weakness. She was diagnosed as NMO with right optic neuritis, longitudinal transverse myelitis, and positive for anti-NMO IgG. The diagnosis of SLE was based on positivity for antinuclear antibody, anti-double stranded DNA, leukopenia, proteinuria. She received intravenous high dose methylprednisolone. Sensory impairment was improved.
Conclusion: To the best of our knowledge, this patient is the first SLE case with NMO satisfied all of Wingerchuck’s criteria.
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KEYWORD
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Neuromyelitis optica, SLE, Optic neuritis
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